/**/

/* Start - Clinic */
/*a.btn-arrow:hover img{ 
 display: none; 
}*/
h1.explore {
  padding-bottom: 2px;
}

p.mandala span {
  padding-left: 5px;
  width: 16px;
}

p.denali span {
  padding-left: 5px;
  width: 16px;
}

p.denali a {
  color: #455e89;
}

.clinic-disease.clinic-disease-block2 {
  background: rgba(235, 239, 238, 0.5);
  padding-top: 70px;
  padding-bottom: 90px;
}

.severetext a {
  color: #830051;
}

#therapeutic-Limitations .burden-disease-block1 .burden-left h1::before, #lung-function-study .burden-disease-block1 .burden-left h1::before {
  width: 111%;
}

#therapeutic-Limitations .burden-disease-block1 .burden-left h2, #lung-function-study .burden-disease-block1 .burden-left h2 {
  font-size: 24px;
  line-height: 28px;
}

.clinic-boxsadow {
  -webkit-box-shadow: 10px 10px 0px 0px rgb(216 223 222);
  -moz-box-shadow: 10px 10px 0px 0px rgba(216, 223, 222, 1);
  border: 1px solid #9db0ac;
  border-radius: 8px;
  padding: 20px;
  color: #413434;
  font-size: 18px;
  line-height: 27px;
  margin-bottom: 40px;
  background: #ffffff;
  margin-left: 50px;
  max-width: 360px;
  margin-left: 0;
  min-height: 330px;
}

.clinical3banner .clinic-boxsadow ul {
  padding-left: 5px;
}

.clinic-boxsadow ul li {
  position: relative;
  padding-left: 10px;
}

p.box-sadowtext1 {
  text-align: left;
  letter-spacing: 0px;
  color: #003864;
  padding-bottom: 10px;
  font-family: "Helvetica Neue";
  font-weight: 500;
  font-size: 20px;
  line-height: 25px;
  padding-top: 10px;
}

.rethink-asthma-block.clinical-box {
  padding-top: 20px;
  padding-bottom: 70px;
}

#therapeutic-Limitations .rethink-section-in, #lung-function-study .rethink-section-in {
  padding: 80px 0 90px 0;
}

p.box-sadow-hyper {
  font-size: 16px;
  line-height: 18px;
  text-decoration: underline;
  padding-top: 15px;
  padding-bottom: 15px;
  color: #455e89;
  font-family: "Helvetica Neue";
}

p.whilepatient {
  text-align: left;
  letter-spacing: 0px;
  color: #003864;
  padding-bottom: 50px;
  font-family: "Helvetica Neue";
  font-size: 20px;
  font-weight: bold;
  line-height: 25px;
  max-width: 840px;
}

.whileline {
  margin-bottom: 70px;
}

.clinic-left {
  display: flex;
}

p.primayend {
  text-align: left;
  letter-spacing: 0px;
  color: #830051;
  opacity: 1;
  padding-bottom: 70px;
  font-size: 24px;
  font-family: "Helvetica Neue";
  font-weight: 500;
  line-height: 28px;
  padding-top: 30px;
}

span.severetext {
  text-decoration: underline;
}

.burden-disease-block1 .burden-section {
  padding: 70px 15px 50px 15px;
}

.albuterol-left {
  width: 39%;
}

.albuterol-right {
  width: 61%;
}

.albuterol-right .desktop-only {
  max-width: 687px;
}

p.albuterol {
  text-align: left;
  letter-spacing: 0px;
  color: #003864;
  width: 54%;
  padding-bottom: 30px;
  font-family: "Helvetica Neue";
  font-weight: bold;
  font-size: 24px;
}

p.significant {
  text-align: left;
  letter-spacing: 0px;
  color: #003864;
  padding-top: 30px;
  font-family: "Helvetica Neue";
  font-size: 20px;
  font-weight: bold;
  max-width: 280px;
  line-height: 25px;
}

p.curvetext {
  padding-top: 40px;
  padding-bottom: 70px;
  font-size: 12.8px;
  font-family: "Helvetica Neue";
  font-weight: normal;
}

p.keysecoundary {
  text-align: left;
  color: #830051;
  font-size: 24px;
  font-weight: 500;
  font-family: "Helvetica Neue";
  padding-bottom: 30px;
  padding-top: 70px;
}

.clinicsecondary {
  display: flex;
  justify-content: space-between;
  padding-bottom: 50px;
}

p.predn {
  padding-bottom: 70px;
  text-align: left;
  letter-spacing: 0px;
  color: #3c4242;
  opacity: 1;
  font-size: 12.8px;
  font-family: "Helvetica Neue";
}

p.aserve {
  text-align: left;
  letter-spacing: 0px;
  color: #3c4242;
  opacity: 1;
  font-size: 12.8px;
  font-family: "Helvetica Neue";
  line-height: 12px;
}

p.saftytext {
  color: #830051;
  font-size: 24px;
  font-family: "Helvetica Neue";
  font-weight: 500;
  padding-top: 70px;
  padding-bottom: 30px;
}

p.summaryreaction {
  color: #003864;
  padding-bottom: 15px;
  font-weight: bold;
  font-size: 20px;
  font-family: "Helvetica Neue";
}

p.datashowing {
  padding-top: 30px;
  padding-bottom: 70px;
  text-align: left;
  letter-spacing: 0px;
  color: #3c4242;
  font-family: "Helvetica Neue";
  font-size: 16px;
  max-width: 829px;
  line-height: 25px;
}

.saftyhr {
  margin-bottom: 70px;
}

p.denalidesign {
  text-align: left;
  color: #003864;
  padding-bottom: 23px;
  padding-top: 70px;
  font-family: Lexia;
  font-size: 30px;
  font-weight: bold;
}

.studydesingimg2 {
  text-align: center;
  margin: 0 auto;
  margin-bottom: 50px;
}

.clinic-left-primary {
  display: flex;
}

.linetwo {
  border: 6px solid #b1c0bd;
  opacity: 0.43;
  background-color: #b1c0bd;
  height: 0px;
  margin-top: 30px;
  max-width: 266px;
}

.lineone {
  border: 3px solid #b1c0bd;
  opacity: 0.43;
  background-color: #b1c0bd;
  height: 0px;
  margin-top: 5px;
  margin-bottom: 30px;
  max-width: 266px;
}

p.efficacydata {
  text-align: left;
  letter-spacing: 0px;
  color: #003864;
  padding-bottom: 50px;
  font-family: "Helvetica Neue";
  font-size: 20px;
  font-weight: bold;
  line-height: 25px;
  max-width: 790px;
}

p.lung {
  text-align: left;
  letter-spacing: 0px;
  color: #830051;
  opacity: 1;
  padding-bottom: 30px;
  font-family: "Helvetica Neue";
  font-size: 24px;
  font-weight: 500;
  padding-top: 30px;
}

p.profiles {
  text-align: left;
  letter-spacing: 0px;
  color: #003864;
  padding-bottom: 50px;
  font-family: "Helvetica Neue";
  font-size: 20px;
  line-height: 28px;
  font-weight: bold;
  max-width: 790px;
}

p.timetext {
  text-align: left;
  letter-spacing: 0px;
  color: #3c4242;
  opacity: 1;
  padding-top: 30px;
  padding-bottom: 30px;
  font-family: "Helvetica Neue";
  font-size: 12.8px;
  line-height: 25px;
}

.summarysafty {
  text-align: left;
  letter-spacing: 0px;
  color: #830051;
  opacity: 1;
  font-size: 24px;
  font-family: "Helvetica Neue";
  font-weight: 500;
  padding-bottom: 30px;
  padding-top: 30px;
}

p.advers {
  text-align: left;
  letter-spacing: 0px;
  color: #003864;
  padding-bottom: 30px;
  font-family: "Helvetica Neue";
  font-size: 20px;
  font-weight: bold;
}

p.theabove {
  text-align: left;
  letter-spacing: 0px;
  color: #3c4242;
  opacity: 1;
  padding-top: 30px;
  padding-bottom: 40px;
  font-size: 16px;
  max-width: 797px;
  font-family: "Helvetica Neue";
  line-height: 25px;
}

.clinic-boxsadow ul li:before {
  content: "";
  position: absolute;
  left: 0;
  width: 4px;
  height: 4px;
  background: #3c4242;
  border-radius: 100%;
  top: 13px;
}

.clinic-boxsadow ul li p {
  font-family: "Helvetica Neue";
  font-weight: normal;
  font-size: 18px;
  line-height: 28px;
}

.clinic-boxsadow ul li.saba {
  margin-left: 10px;
}

.back-to-top {
  display: none;
}

#therapeutic-Limitations .back-to-top, #lung-function-study .back-to-top {
  display: block;
}

.back-to-top {
  position: fixed;
  bottom: 80px;
  right: 70px;
  width: auto;
  z-index: 1;
}

.back-to-top a {
  display: block;
  width: 55px;
  height: 55px;
  background-image: url("/content/dam/intelligentcontent/brands/pt027-medical-hcp-microsite/en/images/desktop/back-to-top.png");
  background-repeat: no-repeat;
  background-size: 55px 55px;
  font-size: 0;
}

.back-to-top a:hover {
  width: 55px;
  height: 55px;
  background-image: url("/content/dam/intelligentcontent/brands/pt027-medical-hcp-microsite/en/images/desktop/back-to-top-hover.png");
  background-repeat: no-repeat;
  background-size: 55px 55px;
}

.border-botom {
  border-bottom: 1px solid #3c4242;
  opacity: 0.5;
}

.border-botom.last {
  margin-bottom: 40px;
}

.border-botom.first {
  margin-bottom: 40px;
}

.rethink-asthma-section.content-container.videotext {
  padding-top: 60px;
}

p.box-sadow-hyper a {
  color: #455e89;
}

.saba1 {
  padding-left: 6px;
}

.rethink-asthma-box.firstbox {
  background-color: #ebefee;
  border: 1px solid #003864;
}

.rethink-asthma-box.first {
  background-color: white;
  border: 1px solid #003864;
}

.rethink-asthma-block.clinic-rescue .rethink-asthma-box {
  border: none;
  background: #ccd7e0;
}

img.header-logo-img-clinc {
  display: none;
}

.top-menu ul.medical-info li.pres {
  display: none;
}

.mobile-only .top-menu ul.medical-info li.pres {
  display: none;
}

#therapeutic-Limitations .top-menu ul.medical-info li.pres, #lung-function-study .top-menu ul.medical-info li.pres {
  display: block;
}

#therapeutic-Limitations .mobile-only .top-menu ul.medical-info li.pres, #lung-function-study .mobile-only .top-menu ul.medical-info li.pres {
  display: block;
}

#therapeutic-Limitations .main-menu-clinc, #lung-function-study .main-menu-clinc {
  background: #003864;
}

#therapeutic-Limitations .header-logo-img, #lung-function-study .header-logo-img {
  display: none;
}

#therapeutic-Limitations .header-logo-img-clinc, #lung-function-study .header-logo-img-clinc {
  display: block;
}

#therapeutic-Limitations .header-main-menu ul li a, #lung-function-study .header-main-menu ul li a {
  color: #ffffff;
}

#therapeutic-Limitations .header-main-menu ul li.sin-up a, #lung-function-study .header-main-menu ul li.sin-up a {
  color: #455e89;
  background: #ffffff;
}

#therapeutic-Limitations .header-main-menu ul li.sin-up a:hover, #lung-function-study .header-main-menu ul li.sin-up a:hover {
  color: #ffffff;
  background: #293852;
}

.burden-right.clinic {
  padding-left: 10%;
}

@media screen and (max-width: 1300px) {
  .burden-right.clinic {
    padding-left: 1%;
  }
}

@media screen and (min-width: 992px) {
  .empty-space {
    height: 160px;
    margin-bottom: 0;
    margin-top: -160px;
    position: relative;
    visibility: hidden;
  }

  p.mandala {
    text-align: left;
    text-decoration: underline;
    letter-spacing: 0px;
    color: #455e89;
    font-size: 24px;
    padding-bottom: 20px;
    padding-top: 30px;
    font-family: "Lexia";
    font-weight: bold;
  }

  p.largetext {
    text-align: left;
    letter-spacing: 0px;
    color: #3c4242;
    padding-bottom: 40px;
    font-family: "Helvetica Neue";
    line-height: 25px;
    font-size: 18px;
    max-width: 438px;
  }

  p.denali {
    text-align: left;
    text-decoration: underline;
    letter-spacing: 0px;
    color: #455e89;
    font-size: 24px;
    padding-bottom: 20px;
    font-family: "Lexia";
    font-weight: bold;
  }

  p.dobletext {
    text-align: left;
    letter-spacing: 0px;
    color: #3c4242;
    font-family: "Helvetica Neue";
    line-height: 25px;
    font-size: 18px;
    max-width: 438px;
  }

  .burden-right.clinic {
    padding-top: 15px;
  }

  p.mandaladesign {
    text-align: left;
    letter-spacing: 0px;
    color: #003864;
    opacity: 1;
    padding-bottom: 23px;
    font-family: Lexia;
    font-weight: bold;
    font-size: 30px;
  }

  p.studydesign {
    text-align: left;
    letter-spacing: 0px;
    color: #830051;
    opacity: 1;
    font-family: "Helvetica Neue";
    font-size: 24px;
    font-weight: 500;
  }

  .clinic-right.studydesingimg {
    text-align: center;
    padding-bottom: 50px;
  }

  .clinical3banner {
    display: flex;
    padding-bottom: 0px;
    justify-content: space-between;
  }

  p.box-sadowtext1 {
    /* text-align: left; */
    /* letter-spacing: 0px; */
    /* color: #003864; */
    /* opacity: 1; */
    /* padding-bottom: 10px; */
    /* font-family: 'Helvetica Neue'; */
    /* font-weight: 500; */
    /* font-size: 20px; */
    /* line-height: 25px; */;
  }

  p.primayend {
    padding-top: 68px;
  }

  p.predn {
    line-height: 25px;
  }

  .border-botom.first {
    margin-bottom: 80px;
  }

  .clinic-disease.clinic-disease-block2 {
    padding-bottom: 130px;
  }

  p.lung {
    padding-top: 60px;
  }

  p.timetext {
    line-height: 20px;
  }

  .summarysafty {
    padding-top: 70px;
  }
}

@media screen and (max-width: 1300px) {
  .clinic-boxsadow {
    max-width: 31.3%;
  }
}

@media screen and (max-width: 991px) {
  #therapeutic-Limitations .header-main-menu ul li a, #lung-function-study {
    color: #003864;
  }

  #therapeutic-Limitations .mobile-only .menu, #lung-function-study .mobile-only .menu {
    background: #ccd7e0;
  }

  #therapeutic-Limitations
    .mobile-only
    .main-menu
    ul.Information-medical-menu::before, #lung-function-study .mobile-only
    .main-menu
    ul.Information-medical-menu::before {
    border-top: 1px solid #003864;
    opacity: 0.7;
  }

  .empty-space {
    height: 74px;
    margin-bottom: 0;
    margin-top: -60px;
    position: relative;
    visibility: hidden;
  }

  .clinic-disease .content-container {
    padding-left: 0px;
    padding-right: 0;
  }

  .clinic-disease.clinic-disease-block3 {
    padding-top: 50px;
  }

  .clinic-disease.clinic-disease-block3 p.denalidesign {
    padding-top: 0px;
  }

  .mandala-eaxc ul li p {
    font-size: 16px;
    line-height: 24px;
  }

  p.box-sadow-hyper {
    font-size: 16px;
    text-decoration: underline;
    padding-top: 10px;
    color: #455e89;
  }

  p.mandala {
    text-align: left;
    text-decoration: underline;
    letter-spacing: 0px;
    color: #455e89;
    font-size: 20px;
    padding-bottom: 12px;
    padding-top: 30px;
    font-family: "Lexia";
    line-height: 25px;
    font-weight: bold;
  }

  p.largetext {
    text-align: left;
    letter-spacing: 0px;
    color: #3c4242;
    padding-bottom: 45px;
    font-family: "Helvetica Neue";
    line-height: 25px;
    font-size: 18px;
  }

  p.denali {
    text-align: left;
    text-decoration: underline;
    letter-spacing: 0px;
    color: #455e89;
    font-size: 19px;
    padding-bottom: 12px;
    font-family: "Lexia";
    font-weight: bold;
  }

  p.dobletext {
    text-align: left;
    letter-spacing: 0px;
    color: #3c4242;
    font-family: "Helvetica Neue";
    line-height: 28px;
    font-size: 18px;
    padding-bottom: 30px;
  }

  .burden-right.clinic {
    padding-left: 2px;
    padding-right: 10px;
    margin-top: 0px;
  }

  p.mandaladesign {
    text-align: left;
    letter-spacing: 0px;
    color: #003864;
    opacity: 1;
    padding-bottom: 23px;
    font-family: Lexia;
    font-weight: bold;
    font-size: 24px;
    padding-left: 15px;
  }

  p.studydesign {
    text-align: left;
    letter-spacing: 0px;
    color: #830051;
    opacity: 1;
    font-family: "Helvetica Neue";
    font-size: 20px;
    font-weight: 500;
    padding-bottom: 30px;
    padding-left: 15px;
  }

  .clinical3banner {
    display: flex;
    padding-bottom: 52px;
    justify-content: space-evenly;
  }

  .clinic-boxsadow {
    margin-left: -7px;
    margin-right: 3px;
    min-height: auto;
    padding: 20px 20px 25px 20px;
    max-width: 100%;
  }

  .clinical3banner {
    display: block;
    padding-bottom: 0px;
    padding-left: 15px;
    margin-right: 15px;
  }

  .clinicsecondary {
    display: block;
    margin: 0;
    text-align: center;
    padding-bottom: 16px;
    padding-left: 15px;
    padding-right: 15px;
  }

  .clinic-right.studydesingimg {
    margin-bottom: 30px;
  }

  .clinic-left-primary {
    display: block;
  }

  p.significant {
    padding-bottom: 30px;
    max-width: 280px;
  }

  .studydesingimg2 {
    margin-top: 30px;
    padding-left: 15px;
    padding-right: 15px;
  }

  .perimage24 {
    margin-bottom: 30px;
  }

  p.lung {
    padding-bottom: 12px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.profiles {
    padding-bottom: 20px;
  }

  .mobileimage {
    margin-bottom: 30px;
    max-width: 100%;
  }

  p.curvetext {
    padding-top: 43px;
    line-height: 20px;
    max-width: 336px;
    padding-bottom: 28px;
  }

  p.keysecoundary {
    padding-top: 35px;
    padding-left: 15px;
    padding-right: 15px;
  }

  .zoom-but {
    position: absolute;
    right: 15px;
    margin-top: -40px;
    width: 44px;
  }

  .back-to-top {
    right: 15px;
  }

  .clinic-right.studydesingimg {
    text-align: center;
    padding-left: 15px;
    padding-right: 15px;
  }

  .perimage24 {
    text-align: center;
  }

  .mobileimage {
    text-align: center;
  }

  .mobileimage1 {
    text-align: center;
    max-width: 100%;
  }

  p.whilepatient {
    padding-bottom: 15px;
    padding-left: 15px;
    padding-right: 15px;
  }

  .whileline {
    margin-bottom: 43px;
  }

  p.primayend {
    padding-bottom: 43px;
    font-size: 20px;
    line-height: 25px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.summaryreaction {
    max-width: 334px;
    line-height: 25px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.datashowing {
    width: 100%;
    padding-bottom: 30px;
  }

  p.efficacydata {
    width: 100%;
    padding-bottom: 20px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.timetext {
    line-height: 19px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.profiles {
    width: 100%;
    line-height: 28px;
    padding-left: 15px;
    padding-right: 15px;
  }

  .summarysafty {
    font-size: 20px;
    line-height: 25px;
    padding-left: 15px;
    padding-right: 15px;
    padding-bottom: 20px;
  }

  p.theabove {
    width: 100%;
    font-size: 12px;
    line-height: 19px;
    padding-top: 28px;
    padding-bottom: 25px;
  }

  h1.explore {
    padding-bottom: 25px;
    margin-left: 10px;
    margin-bottom: 20px;
  }

  .persenimage {
    max-width: 204px;
  }

  p.aserve {
    line-height: 20px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.saftytext {
    padding-bottom: 20px;
    padding-top: 40px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.predn {
    padding-bottom: 25px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.albuterol {
    font-size: 20px;
  }

  p.mandala span {
    width: 16px;
  }

  p.mandala span img {
    width: 16px;
  }

  p.denali span img {
    width: 16px;
  }

  .figureimage {
    width: 100%;
    margin: 0;
  }

  h2.rescue {
    padding-left: 1px;
  }

  .mobile-only.tables {
    text-align: center;
    padding-left: 15px;
    padding-right: 15px;
  }

  .mobile-only.tables img {
    width: 100%;
  }

  .burden-section.content-container.explore {
    padding: 45px 0px 30px 15px;
  }

  h2.airsup {
    right: 9px;
    padding-left: 10px;
    margin-left: 5px;
  }

  .clinic-right.studydesingimg2 img {
    width: 100%;
  }

  .clinicsecondary img {
    width: 100%;
  }

  .clinic-disease.clinic-disease-block2 {
    padding-top: 50px;
    padding-bottom: 40px;
  }

  .albuterol-left {
    width: 100%;
    padding-left: 15px;
    padding-right: 15px;
  }

  .albuterol-right {
    width: 100%;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.denalidesign {
    padding-bottom: 20px;
    padding-left: 15px;
    padding-right: 15px;
  }

  p.advers {
    padding-left: 15px;
    padding-right: 15px;
    line-height: 28px;
    padding-bottom: 20px;
  }

  .rethink-asthma-block.clinical-box {
    padding-top: 0px;
    padding-bottom: 40px;
    border-bottom: rgba(60, 66, 66, 0.5) 1px solid;
    margin-bottom: 50px;
  }

  #therapeutic-Limitations .reframing-main, #lung-function-study .reframing-main {
    width: 100%;
  }

  #therapeutic-Limitations .rethink-section-in, #lung-function-study .rethink-section-in {
    padding: 60px 0 45px 0;
  }

  #therapeutic-Limitations .references-inner, #lung-function-study .references-inner {
    padding-top: 50px;
    margin-bottom: 20px;
  }

  p.box-sadowtext1 {
    padding-bottom: 15px;
    padding-top: 15px;
  }

  .clinic-boxsadow ul li {
    margin: 0 0 5px 0;
  }
}

@media screen and (max-width: 767px) {
  p.primayend {
    max-width: 320px;
  }
}

@media screen and (max-width: 475px) {
  .clinic-rescue .rethink-asthma-box h3 {
    max-width: 220px;
  }
}